TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages.
第一作者:
Lin,Gao
第一单位:
Department of Orthopaedics and Rehabilitation, Center for Musculoskeletal Research, University of Rochester, Rochester, NY, USA.
作者:
主题词
转录激活因子2(Activating Transcription Factor 2);动物(Animals);骨形态发生蛋白质2(Bone Morphogenetic Protein 2);软骨, 关节(Cartilage, Articular);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);软骨细胞(Chondrocytes);细胞外基质(Extracellular Matrix);基因缺失(Gene Deletion);基因表达调控(Gene Expression Regulation);生长面(Growth Plate);MAP激酶激酶激酶类(MAP Kinase Kinase Kinases);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);启动区, 遗传(Promoter Regions, Genetic);蛋白质结合(Protein Binding);蛋白聚糖类(Proteoglycans);SOX9转录因子类(SOX9 Transcription Factor)
DOI
10.1242/jcs.135483
PMID
24144697
发布时间
2021-10-21
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Journal of cell science
5704-13页
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