Possible role of Cdx2 in the serrated pathway of colorectal cancer characterized by BRAF mutation, high-level CpG Island methylator phenotype and mismatch repair-deficiency.
第一作者:
Heather,Dawson
第一单位:
Department of Clinical Pathology, Institute of Pathology, University of Bern, Bern, Switzerland; Translational Research Unit, Institute of Pathology, University of Bern, Bern, Switzerland.
作者:
医学主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);结直肠肿瘤(Colorectal Neoplasms);CpG岛(CpG Islands);DNA甲基化(DNA Methylation);DNA错配修复(DNA Mismatch Repair);DNA突变分析(DNA Mutational Analysis);DNA结合蛋白质类(DNA-Binding Proteins);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);HCT116细胞(HCT116 Cells);HT29细胞(HT29 Cells);同源盒结构域蛋白质类(Homeodomain Proteins);人类(Humans);免疫组织化学(Immunohistochemistry);原位杂交(In Situ Hybridization);男(雄)性(Male);中年人(Middle Aged);MutS同源蛋白2(MutS Homolog 2 Protein);突变(Mutation);核蛋白质类(Nuclear Proteins);原癌基因蛋白质类(Proto-Oncogene Proteins);原癌基因蛋白质B-raf(Proto-Oncogene Proteins B-raf);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));信号传导(Signal Transduction);ras蛋白质类(ras Proteins)
DOI
10.1002/ijc.28564
PMID
24166180
发布时间
2022-03-17
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