Advanced generation anti-prostate specific membrane antigen designer T cells for prostate cancer immunotherapy.

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作者： Qiangzhong,Ma ^[1] ; Erica M,Gomes ; Agnes Shuk-Yee,Lo ; Richard P,Junghans

作者单位： Department of Medicine, Biotherapeutics Development Lab, Roger Williams Medical Center, Boston University School of Medicine, Providence, Rhode Island. ^[1]

关键词 CD28 PSMA chimeric antigen receptor gene therapy lymphodepletion non-myeloablative (NMA) conditioning

主题词动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);细胞系, 肿瘤(Cell Line, Tumor);细胞膜(Cell Membrane);细胞毒性, 免疫(Cytotoxicity, Immunologic);遗传载体(Genetic Vectors);人类(Humans);免疫疗法, 过继(Immunotherapy, Adoptive);干扰素γ(Interferon-gamma);白细胞介素2(Interleukin-2);Jurkat细胞(Jurkat Cells);淋巴细胞活化(Lymphocyte Activation);男(雄)性(Male);小鼠(Mice);小鼠, 裸(Mice, Nude);前列腺(Prostate);前列腺肿瘤(Prostatic Neoplasms);受体, 抗原(Receptors, Antigen);受体, 抗原, T细胞(Receptors, Antigen, T-Cell);重组融合蛋白质类(Recombinant Fusion Proteins);逆转录病毒科(Retroviridae);T淋巴细胞(T-Lymphocytes);转导, 遗传(Transduction, Genetic);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1002/pros.22749

PMID 24174378

发布时间 2018-12-03

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The Prostate

2014年74卷3期

286-96页

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Advanced generation anti-prostate specific membrane antigen designer T cells for prostate cancer immunotherapy.

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Advanced generation anti-prostate specific membrane antigen designer T cells for prostate cancer immunotherapy.

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The Prostate

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