换一批
换一批The discovery of novel N-(2-pyrimidinylamino) benzamide derivatives as potent hedgehog signaling pathway inhibitors.
第一作者：
Minhang,Xin
第一单位：
Jiangsu Simcere Pharmaceutical Co. Ltd, Jiangsu Key Laboratory of Molecular Targeted Antitumor Drug Research, No. 699-18, Xuan Wu District, Nanjing 210042, PR China. Electronic address: xmhcpu@163.com.
作者：
主题词
动物(Animals);苯甲酰胺类(Benzamides);药物设计(Drug Design);药物评价, 临床前(Drug Evaluation, Preclinical);半衰期(Half-Life);猬蛋白质类(Hedgehog Proteins);嘧啶类(Pyrimidines);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);信号传导(Signal Transduction);构效关系(Structure-Activity Relationship)
DOI
10.1016/j.bmcl.2013.10.022
PMID
24176396
发布时间
2013-12-02
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