第一作者:
Limin,Wang
第一单位:
Department of Radiology, University of Pennsylvania, Philadelphia, PA19104, USA.
作者:
关键词
(18)F2-[(18)F]fluoro-2-deoxy-d-glucose2-amino-bicylo[2.2.1]heptane-2-carboxylic acid3-[(123)I]iodo-alpha-methyl-l-tyrosine3-[(18)F]fluoro-cyclobutyl-1-carboxylic acid6-[(18)F]fluoro-3,4-dihydroxyphenylalanineASCASCT2AcFETBCHFACBCFCFDGFDOPAFETFET-AlaFET-GlyHPLCHRMSIMTImaging agentN-acetyl O-(2-[(18)F]fluoroethyl)-l-tyrosineO-(2-[(18)F]fluoroethyl)-l-tyrosineO-(2-[(18)F]fluoroethyl)-l-tyrosyl-l-alanineO-(2-[(18)F]fluoroethyl)-l-tyrosyl-l-glycinePBSPEPTsPETPeptideProdrugSPETFAalanine-serine-cysteine preferring amino acid transporter systemflash chromatographyhigh performance liquid chromatographyhigh-resolution mass spectrometrypeptide transportersphosphate buffered salinesolid-phase extractionsystem ASC transporter subtype 2trifluoroacetic acid
医学主题词
酰胺基水解酶类(Amidohydrolases);动物(Animals);生物转运(Biological Transport);脑肿瘤(Brain Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);二肽酶类(Dipeptidases);人类(Humans);水解作用(Hydrolysis);正电子发射断层显像术(Positron-Emission Tomography);药物前体(Prodrugs);大鼠(Rats);酪氨酸(Tyrosine)
DOI
10.1016/j.nucmedbio.2013.09.011
PMID
24183614
发布时间
2021-10-21
基金项目
R01 CA164490/CA/NCI NIH HHS/United States
CA-164490/CA/NCI NIH HHS/United States
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