换一批Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas.
第一作者：
Sebastian,Bender
第一单位：
Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
作者：
医学主题词
脑肿瘤(Brain Neoplasms);脑干肿瘤(Brain Stem Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);儿童(Child);DNA甲基化(DNA Methylation);后成说, 遗传(Epigenesis, Genetic);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因, 显性(Genes, Dominant);胶质母细胞瘤(Glioblastoma);组蛋白赖氨酸N-甲基转移酶(Histone-Lysine N-Methyltransferase);组蛋白类(Histones);人类(Humans);甲基化(Methylation);分子序列数据(Molecular Sequence Data);突变, 误义(Mutation, Missense);肿瘤蛋白质类(Neoplasm Proteins);蛋白质结合(Protein Binding);蛋白质加工, 转译后(Protein Processing, Post-Translational);转录因子(Transcription Factors);转录, 遗传(Transcription, Genetic)
DOI
10.1016/j.ccr.2013.10.006
PMID
24183680
发布时间
2022-04-09
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Cancer cell
660-72页
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