换一批
换一批Mechanisms of enhanced neutralization of botulinum neurotoxin by monoclonal antibodies conjugated to antibodies specific for the erythrocyte complement receptor.
作者：
关键词
BoNTBoNT/ABoNT/A recombinant 50kD C-terminal domainBotulinum neurotoxinCR1FPFab′HC50AHPHRPHeteropolymerImmune adherenceMonoclonal antibodyNMJOPDPBSPeritoneal macrophageRBCsRI-BoNTToxin clearanceType 1 complement receptora fusion protein consisting of a streptavidin molecule and an scFv specific for glycophorinbotulinum neurotoxincomplement receptorhCR1heteropolymerhorseradish peroxidasehuman complement receptori.p.i.v.intra-peritonealintravenousmAbmAb antigen binding domainmonoclonal antibodyneuromuscular junctiono-phenylenediamine dihydrochloridephosphate buffered salinerecombinant inactive BoNTred blood cellsscFvserotype A botulinum neurotoxinsingle-chain variable fragment
主题词
动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);抗体, 中和(Antibodies, Neutralizing);抗原抗体复合物(Antigen-Antibody Complex);肉毒毒素类(Botulinum Toxins);肉毒中毒(Botulism);红细胞(Erythrocytes);人类(Humans);巨噬细胞(Macrophages);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);受体, 补体(Receptors, Complement);受体, 补体3b(Receptors, Complement 3b)
DOI
10.1016/j.molimm.2013.09.005
PMID
24184879
发布时间
2021-10-21
- 浏览47
Molecular immunology
247-54页
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