换一批Glycidol induces axonopathy and aberrations of hippocampal neurogenesis affecting late-stage differentiation by exposure to rats in a framework of 28-day toxicity study.
第一作者：
Hirotoshi,Akane
第一单位：
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo 183-8509, Japan.
作者：
关键词
3,3′-diaminobenzidineAxonopathyC(T)Calb1Calb2Calbindin-D-28KCalretininDABDCXDihydropyrimidinase-like 3DoublecortinDpysl3GABAGFAPGamma-aminobutyric acidGapdhGlial fibrillary acidic proteinGlyceraldehyde 3-phosphate dehydrogenaseGlycidolHippocampal dentate gyrusHprtHypoxanthine phosphoribosyltransferase 1MMIMethimazoleNF-LNeuNNeurofilament-LNeurogenesisNeuron-specific nuclear proteinNeurotoxicityPBSPCNAPaired box 6ParvalbuminPax6Phosphate-buffered salinePhosphorylated neurofilament-HProliferating cell nuclear antigenPvalbRT-PCRReverse-transcription polymerase chain reactionSGZSubgranular zoneT box brain 2T(3)T(4)TSHTUNELTbr2Terminal deoxynucleotidyl transferase dUTP nick end labelingThreshold cycleThyroid-stimulating hormoneThyroxineTriiodothyroninep-NF-H
医学主题词
动物(Animals);抗原, 核(Antigens, Nuclear);细胞凋亡(Apoptosis);轴突(Axons);致癌物(Carcinogens);细胞计数(Cell Count);细胞分化(Cell Differentiation);齿状回(Dentate Gyrus);环氧化合物(Epoxy Compounds);女(雌)性(Female);步态障碍, 神经性(Gait Disorders, Neurologic);海马(Hippocampus);激素类(Hormones);免疫组织化学(Immunohistochemistry);中间神经元(Interneurons);神经组织蛋白质类(Nerve Tissue Proteins);神经发生(Neurogenesis);妊娠(Pregnancy);产前暴露迟发效应(Prenatal Exposure Delayed Effects);丙醇类(Propanols);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);干细胞(Stem Cells);甲状腺激素类(Thyroid Hormones)
DOI
10.1016/j.toxlet.2013.10.026
PMID
24185127
发布时间
2021-12-03
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Toxicology letters
424-32页
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