Exendin-4 protects mitochondria from reactive oxygen species induced apoptosis in pancreatic Beta cells.-论文-万方医学网

作者： Zhen,Li ^[1] ; Zhiguang,Zhou ; Gan,Huang ; Fang,Hu ; Yufei,Xiang ; Lining,He

作者单位： Diabetes Center, Second Xiangya Hospital, and Institute of Metabolism and Endocrinology, Key Laboratory of Diabetes Immunology, Ministry of Education, Central South University, Changsha, China. ^[1]

主题词动物(Animals);细胞凋亡(Apoptosis);凋亡调节蛋白质类(Apoptosis Regulatory Proteins);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);细胞系(Cell Line);DNA碎片裂(DNA Fragmentation);酶激活(Enzyme Activation);脂肪酸类(Fatty Acids);基因表达调控(Gene Expression Regulation);Ⅵ型磷脂酶A2(Group VI Phospholipases A2);降血糖药(Hypoglycemic Agents);胰岛素分泌细胞(Insulin-Secreting Cells);膜电位, 线粒体(Membrane Potential, Mitochondrial);小鼠(Mice);线粒体(Mitochondria);氧化性应激(Oxidative Stress);肽类(Peptides);磷脂酶A2, 胞质型(Phospholipases A2, Cytosolic);活性氧(Reactive Oxygen Species);时间因素(Time Factors);转录, 遗传(Transcription, Genetic);毒液类(Venoms)

DOI 10.1371/journal.pone.0076172

PMID 24204601

发布时间 2021-10-21

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Exendin-4 protects mitochondria from reactive oxygen species induced apoptosis in pancreatic Beta cells.

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Exendin-4 protects mitochondria from reactive oxygen species induced apoptosis in pancreatic Beta cells.

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