Development of a method to measure free and bound ropivacaine in human plasma using equilibrium dialysis and hydrophilic interaction chromatography coupled to high resolution mass spectrometry.
第一作者:
Muhammad,Abbas
第一单位:
Strathclyde Institute of Pharmaceutical and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, United Kingdom.
作者:
医学主题词
酰胺类(Amides);麻醉药, 局部(Anesthetics, Local);关节成形术, 置换, 髋(Arthroplasty, Replacement, Hip);关节成形术, 置换, 膝(Arthroplasty, Replacement, Knee);校准(Calibration);导管(Catheters);色谱法, 液相(Chromatography, Liquid);透析(Dialysis);人类(Humans);亲水和疏水相互作用(Hydrophobic and Hydrophilic Interactions);利多卡因(Lidocaine);质谱分析法(Mass Spectrometry);血清类黏蛋白(Orosomucoid);蛋白质结合(Protein Binding);结果可重复性(Reproducibility of Results)
DOI
10.1016/j.talanta.2013.08.049
PMID
24209310
发布时间
2018-12-02
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