换一批Design, synthesis and evaluation of a cellular stable and detectable biotinylated fumagillin probe and investigation of cell permeability of fumagillin and its analogs to endothelial and cancer cells.
第一作者：
Guo-Chun,Zhou
第一单位：
School of Pharmaceutical Sciences and College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 211816, Jiangsu, China. Electronic address: gczhou@njut.edu.cn.
作者：
关键词
AngiogenesisBiotinylated fumagillinBocCancer cellCell permeabilityDPPAEndothelial cellFumagillinHRPHUVECMetAP2NGGMYCMLYOUNGM-AFISTTPQSA-NTFAUHODULUFNVILLN-XAIMPBHRSA-NZEHZTKZKPCSXTC-SQKMCSLSSA-Ndiphenylphosphoryl azideeukaryotic methionine aminopeptidase type IIhorseradish peroxidasehuman umbilical vein endothelial cellst-butoxycarbonyltrifluoroacetic acid
医学主题词
生物素化作用(Biotinylation);细胞系, 肿瘤(Cell Line, Tumor);细胞膜通透性(Cell Membrane Permeability);细胞增殖(Cell Proliferation);环己烷类(Cyclohexanes);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物设计(Drug Design);脂肪酸类, 不饱和(Fatty Acids, Unsaturated);Hep G2细胞(Hep G2 Cells);人类(Humans);分子结构(Molecular Structure);倍半萜类(Sesquiterpenes);构效关系(Structure-Activity Relationship)
DOI
10.1016/j.ejmech.2013.10.033
PMID
24211639
发布时间
2013-12-09
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