Synthetic lethality between CCNE1 amplification and loss of BRCA1.

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作者： Dariush,Etemadmoghadam ^[1] ; Barbara A,Weir ; George,Au-Yeung ; Kathryn,Alsop ; Gillian,Mitchell ; Joshy,George ; Australian Ovarian Cancer Study Group ; Sally,Davis ; Alan D,D'Andrea ; Kaylene,Simpson ; William C,Hahn ; David D L,Bowtell

作者单位： Department of Research, Peter MacCallum Cancer Centre, East Melbourne, VIC 3002, Australia. ^[1]

关键词 CDK2 DNA repair RNAi cell cycle pan-cancer

主题词抗肿瘤药(Antineoplastic Agents);BRCA1蛋白质(BRCA1 Protein);硼酸化物(Boronic Acids);细胞周期蛋白E(Cyclin E);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);微阵列分析(Microarray Analysis);癌基因蛋白质类(Oncogene Proteins);卵巢肿瘤(Ovarian Neoplasms);蛋白酶体内肽酶复合物(Proteasome Endopeptidase Complex);吡嗪类(Pyrazines);RNA, 小分子干扰(RNA, Small Interfering)

DOI 10.1073/pnas.1314302110

PMID 24218601

发布时间 2021-10-21

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Proceedings of the National Academy of Sciences of the United States of America

2013年110卷48期

19489-94页

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Synthetic lethality between CCNE1 amplification and loss of BRCA1.

Proceedings of the National Academy of Sciences of the United States of America

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Proceedings of the National Academy of Sciences of the United States of America

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Synthetic lethality between CCNE1 amplification and loss of BRCA1.

Proceedings of the National Academy of Sciences of the United States of America

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Proceedings of the National Academy of Sciences of the United States of America

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