Bisphenol A promotes dendritic morphogenesis of hippocampal neurons through estrogen receptor-mediated ERK1/2 signal pathway.
作者:
关键词
17beta-estradiol17β-E(2)AdV-EGFPBPABSABisphenol ACNSCdc42DABDMEMDMSODulbecco’s Modified Eagle MediumECLERERK1/2ERKsEstrogen receptorF-actinFBSGPR30Gprotein-coupled receptor 30Hippocampal neuronsMAPKMEKMorphogenesisN-methyl-d-aspartateN-methyl-d-aspartate receptor subunit 2BNMDANR2BPBSPBS/Tween-20PBSTPMSFRac1Ras homologous ARas related C3 botulinum toxinsubstrate 1Rho ARhoA and Rac1/Cdc42SDS–PAGESEMbisphenol Abovine serum albumincell divisioncycle 42central nervous systemdiaminobenzidinedimethyl sulfoxideenhanced chemiluminescenceestrogen receptorextracellular signal-regulated kinase 1/2fetal bovine serumfilamentous actinmitogen-activated ERK-activating kinasemitogen-activated protein kinasepNR2Bphenylmethanesulfonyl fluoridephosphate buffered salinephosphorylated N-methyl-d-aspartate receptor subunit 2Bsodium lauryl sulfate–polyacrylamide gel electrophoresisstandard error of meanthe recombinant adenovirus encoding enhanced green fluorescent protein
主题词
动物(Animals);二苯甲基化合物(Benzhydryl Compounds);树突(Dendrites);内分泌干扰物(Endocrine Disruptors);雌二醇(Estradiol);雌激素受体α(Estrogen Receptor alpha);女(雌)性(Female);海马(Hippocampus);MAP激酶信号系统(MAP Kinase Signaling System);形态发生(Morphogenesis);神经元(Neurons);酚类(Phenols);磷酰化(Phosphorylation);大鼠(Rats);受体, 雌激素(Receptors, Estrogen);受体, N-甲基-D-天冬氨酸(Receptors, N-Methyl-D-Aspartate)
DOI
10.1016/j.chemosphere.2013.09.063
PMID
24231043
发布时间
2021-08-16
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Chemosphere
129-37页
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