换一批FATS is an E2-independent ubiquitin ligase that stabilizes p53 and promotes its activation in response to DNA damage.
第一作者：
S,Yan
第一单位：
1] Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China [2] Key Laboratory of Breast Cancer Prevention and Therapy, Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
作者：
医学主题词
细胞系(Cell Line);细胞支架蛋白质类(Cytoskeletal Proteins);DNA损伤(DNA Damage);人类(Humans);蛋白质稳定性(Protein Stability);蛋白质结构, 三级(Protein Structure, Tertiary);原癌基因蛋白质c-mdm2(Proto-Oncogene Proteins c-mdm2);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);泛素化(Ubiquitination)
DOI
10.1038/onc.2013.494
PMID
24240685
发布时间
2016-11-25
- 浏览18
Oncogene
5424-33页
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