换一批
换一批Toll-like receptor-2 mediates adaptive cardiac hypertrophy in response to pressure overload through interleukin-1β upregulation via nuclear factor κB activation.
作者：
主题词
适应, 生理学(Adaptation, Physiological);动物(Animals);主动脉(Aorta);骨髓移植(Bone Marrow Transplantation);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);收缩(Constriction);疾病模型, 动物(Disease Models, Animal);内皮细胞(Endothelial Cells);成纤维细胞(Fibroblasts);纤维化(Fibrosis);HSP70热休克蛋白质类(HSP70 Heat-Shock Proteins);人类(Humans);肥大, 左心室(Hypertrophy, Left Ventricular);胰岛素样生长因子Ⅰ(Insulin-Like Growth Factor I);白细胞介素1β(Interleukin-1beta);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);心肌炎(Myocarditis);心肌(Myocardium);NF-κB(NF-kappa B);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);信号传导(Signal Transduction);时间因素(Time Factors);Toll样受体2(Toll-Like Receptor 2);增量调节(Up-Regulation);心室功能障碍, 左(Ventricular Dysfunction, Left);心室功能, 左(Ventricular Function, Left);心室重构(Ventricular Remodeling)
DOI
10.1161/JAHA.113.000267
PMID
24249711
发布时间
2023-11-20
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