Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.
第一作者:
Anna C,Navis
第一单位:
Department of Pathology, Radboud University Nijmegen Medical Centre, PO Box 9101, Nijmegen, 6500 HB, The Netherlands. W.Leenders@pathol.umcn.nl.
作者:
医学主题词
动物(Animals);脑(Brain);脑肿瘤(Brain Neoplasms);细胞, 培养的(Cells, Cultured);女(雌)性(Female);戊二酸盐类(Glutarates);人类(Humans);异柠檬酸脱氢酶(Isocitrate Dehydrogenase);酮戊二酸类(Ketoglutaric Acids);小鼠, 近交BALB C(Mice, Inbred BALB C);线粒体(Mitochondria);突变, 误义(Mutation, Missense);肿瘤移植(Neoplasm Transplantation);少突神经胶质瘤(Oligodendroglioma)
DOI
10.1186/2051-5960-1-18
PMID
24252742
发布时间
2022-04-08
- 浏览18
Acta neuropathologica communications
2013年1卷
18页
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