换一批
换一批Pre-clinical safety evaluation of the synthetic human milk, nature-identical, oligosaccharide 2'-O-Fucosyllactose (2'FL).
第一作者：
Myriam,Coulet
第一单位：
Nestlé Research Center, Vers-chez-les-Blanc, PO Box 44, 1000 Lausanne 26, Switzerland. Electronic address: myriam.coulet@rdls.nestle.com.
作者：
关键词
2-Fucosyllactose2′-O-Fucosyllactose2′FLAG ratioALATALPASATAlbBiliCPCaCholCreatDRFFOSGOSGavageGlobHMOHbHuman milk oligosaccharideIFInfant formulaJuvenile ratsKLNnTMCHMCHCMCVMFMLAMMSMoEMutagenicityNOAELNaNo Observed Adverse Effect LevelPCVPNDProtRBCRSRTGRetiSafetySub-chronic toxicityTFTTKWBCalanine amino-transferasealbuminalbumin/globulin ratioalkaline phosphataseaspartate aminotransferasecalciumcreatininecyclophosphamidedose range findingfructooligosaccharidegalactooligosaccharideglobulinhemoglobinhuman milk oligosaccharideinfant formulaelacto-N-neotetraosemargin of exposuremean corpuscular hemoglobinmean corpuscular hemoglobin concentrationmean corpuscular volumemethyl methanesulfonatemouse lymphoma assaymutant frequency for 10(6)cellspack cell volumepostnatal daypotassiumred blood cellsrelative survivalrelative total growthreticulocytessodiumthymidine kinasetotal bilirubintotal cholesteroltotal proteintrifluorothymidinewhite blood cells
主题词
动物(Animals);动物, 新生(Animals, Newborn);细胞系, 肿瘤(Cell Line, Tumor);女(雌)性(Female);人类(Humans);婴儿配方(Infant Formula);男(雄)性(Male);小鼠(Mice);乳, 人(Milk, Human);诱变力试验(Mutagenicity Tests);大鼠(Rats);大鼠, Wistar(Rats, Wistar);鼠伤寒沙门菌(Salmonella typhimurium);三糖类(Trisaccharides)
DOI
10.1016/j.yrtph.2013.11.005
PMID
24262411
发布时间
2017-11-16
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