Neuromedin U receptor 2 knockdown in the paraventricular nucleus modifies behavioral responses to obesogenic high-fat food and leads to increased body weight.
第一作者:
C R,Benzon
第一单位:
Center for Addiction Research, Department of Pharmacology & Toxicology, University of Texas Medical Branch, United States.
作者:
关键词
4’,6-diamidino-2-phenylindoleAAVDAPIGFPNMUNMUR2PVNROadeno-associated virusbinge eatingdietary fatfeeding behaviorgreen fluorescent proteinneuromedin Uneuromedin U receptor 2obesityparaventricular nucleusreverse osmosisshCTRLshNMUR2shRNAsmall hairpin NMUR2 knockdown RNAsmall hairpin RNAsmall hairpin control (non-silencing) RNAviral RNA interference
主题词
动物(Animals);体重(Body Weight);膳食脂肪类(Dietary Fats);进食(Eating);摄食行为(Feeding Behavior);偏食(Food Preferences);基因敲低技术(Gene Knockdown Techniques);免疫组织化学(Immunohistochemistry);男(雄)性(Male);运动活动(Motor Activity);下丘脑室旁核(Paraventricular Hypothalamic Nucleus);RNA, 小分子干扰(RNA, Small Interfering);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);受体, 神经递质(Receptors, Neurotransmitter);蔗糖(Sucrose);体重增长(Weight Gain)
DOI
10.1016/j.neuroscience.2013.11.023
PMID
24269937
发布时间
2021-10-21
- 浏览70
Neuroscience
270-9页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文