换一批
换一批Arsenite binding-induced zinc loss from PARP-1 is equivalent to zinc deficiency in reducing PARP-1 activity, leading to inhibition of DNA repair.
第一作者：
Xi,Sun
第一单位：
Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
作者：
关键词
4-(2-Pyridylazo)-resorcinol monosodium salt8-OHdG8-hydroxyl-2′-deoxyguanineArseniteCD spectrumDNA damage repairICP/AESN,N,N′,N′-tetrakis(2-pyridylmethyl) ethylenediaminePARPARP-1PMSFTECPTPENTris (2-carboxyethyl) phosphineUVRZinc deficiencyZinc fingercircular dichroism spectruminductively coupled plasma atomic emission spectroscopyphenylmethylsulfonyl fluoridepoly(ADP-ribose) polymerase-1ultraviolet radiationzfzinc finger
主题词
亚砷酸盐类(Arsenites);细胞系(Cell Line);螯合剂(Chelating Agents);DNA损伤(DNA Damage);DNA修复(DNA Repair);脱氧鸟苷(Deoxyguanosine);乙二胺类(Ethylenediamines);人类(Humans);聚ADP核糖聚合酶类(Poly(ADP-ribose) Polymerases);紫外线(Ultraviolet Rays);锌(Zinc);锌指(Zinc Fingers)
DOI
10.1016/j.taap.2013.11.010
PMID
24275069
发布时间
2021-10-21
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