Exonuclease 1 is essential for maintaining genomic stability and the proliferative capacity of neural but not hematopoietic stem cells.
第一作者:
Junling,Zhang
第一单位:
Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China; Institute of Aging Research, School of Medicine, Hangzhou Normal University School of Medicine, Hangzhou, China.
作者:
医学主题词
动物(Animals);细胞增殖(Cell Proliferation);周期素依赖激酶抑制剂p21(Cyclin-Dependent Kinase Inhibitor p21);DNA损伤(DNA Damage);DNA修复(DNA Repair);脱氧核糖核酸外切酶类(Exodeoxyribonucleases);基因组不稳定性(Genomic Instability);造血干细胞(Hematopoietic Stem Cells);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);神经干细胞(Neural Stem Cells);嗅球(Olfactory Bulb);活性氧(Reactive Oxygen Species);增量调节(Up-Regulation)
DOI
10.1016/j.scr.2013.11.001
PMID
24280419
发布时间
2016-05-18
- 浏览11
Stem cell research
250-9页
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