Induction of innate immunity by Aspergillus fumigatus cell wall polysaccharides is enhanced by the composite presentation of chitin and beta-glucan.
第一作者:
Lalit Kumar,Dubey
第一单位:
Institute of Molecular Medicine, Department of Cardiovascular and Renal Research, University of Southern Denmark, DK-5000 Odense, Denmark.
作者:
关键词
A. fumigatusABPAAIFAMCaseAspergillus fumigatusBALChitinFReDFungal cell wall polysaccharidesGlcNAcInflammationInnate immunityLungN-acetylglucosaminePAMPsPRRsacidic mammalian chitinasealkali-insoluble cell wall fragmentsallergic bronchopulmonary aspergillosisbronchoalveolar lavagefibrinogen-related domainpathogen-associated molecular patternspattern recognition receptorsβ-Glucan
主题词
投药, 鼻内(Administration, Intranasal);动物(Animals);曲霉菌病(Aspergillosis);烟曲霉菌(Aspergillus fumigatus);细胞运动(Cell Movement);细胞壁(Cell Wall);壳多糖(Chitin);细胞因子类(Cytokines);药物协同作用(Drug Synergism);嗜酸细胞(Eosinophils);女(雌)性(Female);免疫, 先天(Immunity, Innate);肺(Lung);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);中性白细胞(Neutrophils);受体, 模式识别(Receptors, Pattern Recognition);β葡聚糖类(beta-Glucans)
DOI
10.1016/j.imbio.2013.10.003
PMID
24286790
发布时间
2016-11-25
- 浏览56

Immunobiology
179-88页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文