Ghrelin protects human umbilical vein endothelial cells against high glucose-induced apoptosis via mTOR/P70S6K signaling pathway.

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第一作者： Jianhua,Zhu

第一单位： Laboratory of Clinical Immunology, Wuhan No. 1 Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, Hubei, PR China.

作者： Jianhua,Zhu ^[1] ; Chenghong,Zheng ^[2] ; Jie,Chen ^[1] ; Jing,Luo ^[3] ; Bintao,Su ^[1] ; Yan,Huang ^[1] ; Wen,Su ^[1] ; Zixi,Li ^[1] ; Tianpen,Cui ^[4]

作者单位： Laboratory of Clinical Immunology, Wuhan No. 1 Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, Hubei, PR China. ^[1] Laboratory of Clinical Immunology, Wuhan No. 1 Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, Hubei, PR China; Department of Endocrinology, Wuhan No. 1 Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, Hubei, PR China. ^[2] Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, Hubei, PR China. ^[3] Laboratory of Clinical Immunology, Wuhan No. 1 Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, Hubei, PR China. Electronic address: tianpencui@hotmail.com. ^[4]

关键词 Apoptosis GHS-R1a Ghrelin mTOR/P70S6K

主题词细胞凋亡(Apoptosis);胃促生长素(Ghrelin);葡萄糖(Glucose);人类(Humans);磷酰化(Phosphorylation);核糖体蛋白质S6激酶类, 70-kDa(Ribosomal Protein S6 Kinases, 70-kDa);信号传导(Signal Transduction);甜味剂(Sweetening Agents);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);bcl-2相关X蛋白质(bcl-2-Associated X Protein)

DOI 10.1016/j.peptides.2013.11.015

PMID 24287118

发布时间 2021-12-03

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Ghrelin protects human umbilical vein endothelial cells against high glucose-induced apoptosis via mTOR/P70S6K signaling pathway.

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Ghrelin protects human umbilical vein endothelial cells against high glucose-induced apoptosis via mTOR/P70S6K signaling pathway.

Peptides

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Peptides

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