Repeated forced swim stress enhances CFA-evoked thermal hyperalgesia and affects the expressions of pCREB and c-Fos in the insular cortex.
第一作者:
H,Imbe
第一单位:
Department of Physiology, Wakayama Medical University, Kimiidera 811-1, Wakayama City 641-8509, Japan. Electronic address: imbe@wakayama-med.ac.jp.
作者:
关键词
ACCAICANOVABSACFAFSICIEGIRPAGPBPFAPICPWLRAICRTRVMSIHTBSTTBSTris-buffered salineTris-buffered saline containing 0.1 Tween-20analysis of varianceanterior cingulate cortexanterior insular cortexbovine serum albuminc-Foscomplete Freund’s adjuvantforced swim stresshyperalgesiaimmediate early geneimmunoreactiveinsular cortexpCREBparaformaldehydepaw withdrawal latencyperiaqueductal gray matterphosphate bufferphospho-cAMP response element-binding proteinposterior insular cortexroom temperaturerostral agranular insular cortexrostral ventromedial medullastress-induced hyperalgesia
医学主题词
动物(Animals);CREB结合蛋白质(CREB-Binding Protein);大脑皮质(Cerebral Cortex);疾病模型, 动物(Disease Models, Animal);Freund佐剂(Freund's Adjuvant);功能偏侧化(Functional Laterality);痛觉过敏(Hyperalgesia);炎症(Inflammation);男(雄)性(Male);疼痛测定(Pain Measurement);痛阈(Pain Threshold);原癌基因蛋白质c-fos(Proto-Oncogene Proteins c-fos);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);应激, 心理学(Stress, Psychological);游泳(Swimming)
DOI
10.1016/j.neuroscience.2013.11.045
PMID
24291670
发布时间
2014-01-22
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Neuroscience
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