Human iPSC-based modeling of late-onset disease via progerin-induced aging.-论文-万方医学网

作者： Justine D,Miller ^[1] ; Yosif M,Ganat ; Sarah,Kishinevsky ; Robert L,Bowman ; Becky,Liu ; Edmund Y,Tu ; Pankaj K,Mandal ; Elsa,Vera ; Jae-won,Shim ; Sonja,Kriks ; Tony,Taldone ; Noemi,Fusaki ; Mark J,Tomishima ; Dimitri,Krainc ; Teresa A,Milner ; Derrick J,Rossi ; Lorenz,Studer

作者单位： The Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10065, USA; Developmental Biology Program, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10065, USA; Gerstner Sloan-Kettering Graduate School, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10065, USA. ^[1]

主题词成年人(Adult);发病年龄(Age of Onset);老年人(Aged);老年人, 80以上(Aged, 80 and over);衰老(Aging);动物(Animals);细胞分化(Cell Differentiation);儿童(Child);成纤维细胞(Fibroblasts);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);核纤层蛋白A型(Lamin Type A);中脑(Mesencephalon);小鼠(Mice);中年人(Middle Aged);模型, 生物学(Models, Biological);核蛋白质类(Nuclear Proteins);帕金森病(Parkinson Disease);表型(Phenotype);蛋白质前体(Protein Precursors);组织供者(Tissue Donors)

DOI 10.1016/j.stem.2013.11.006

PMID 24315443

发布时间 2025-01-04

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Human iPSC-based modeling of late-onset disease via progerin-induced aging.

Cell stem cell

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Human iPSC-based modeling of late-onset disease via progerin-induced aging.

Cell stem cell

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Cell stem cell

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