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Donepezil treatment of older adults with cognitive impairment and depression (DOTCODE study): clinical rationale and design.

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第一作者： Gregory H,Pelton

第一单位： Division of Geriatric Psychiatry, New York State Psychiatric Institute, NY, USA; Department of Psychiatry, College of Physicians and Surgeons, Columbia University, NY, USA.

作者： Gregory H,Pelton ^[1] ; Howard,Andrews ^[1] ; Steven P,Roose ^[1] ; Sue M,Marcus ^[2] ; Kristina,D'Antonio ^[3] ; Hala,Husn ^[4] ; Jeffrey R,Petrella ^[5] ; Anthony S,Zannas ^[4] ; P Murali,Doraiswamy ^[6] ; D P,Devanand ^[1]

作者单位： Division of Geriatric Psychiatry, New York State Psychiatric Institute, NY, USA; Department of Psychiatry, College of Physicians and Surgeons, Columbia University, NY, USA. ^[1] Department of Psychiatry, College of Physicians and Surgeons, Columbia University, NY, USA; Department of Biostatistics, Mailman School of Public Health, Columbia University, NY, USA. ^[2] Division of Geriatric Psychiatry, New York State Psychiatric Institute, NY, USA. ^[3] Department of Psychiatry, Duke University Medical Center, Durham, NC, USA. ^[4] Department of Radiology, Duke University Medical Center, Durham, NC, USA. ^[5] Department of Psychiatry, Duke University Medical Center, Durham, NC, USA; Department of Medicine, Duke University Medical Center, Durham, NC, USA; Department of Duke Institute for Brain Sciences, Duke University Medical Center, Durham, NC, USA. ^[6]

关键词 Aging Alzheimer's disease Cognitive impairment Depression Donepezil Memory decline Randomized clinical trial