换一批Estrogen attenuates lipopolysaccharide-induced nitric oxide production in macrophages partially via the nongenomic pathway.
第一作者：
Limin,Liu
第一单位：
Departments of Pathology and Pathophysiology, Medical College of Soochow University, Suzhou 215123, Jiangsu, China.
作者：
关键词
17β-estradiolAP-1BMMsE(2)E(2) conjugated to bovine serum albuminE(2)–BSAERK1/2EstrogenIκBJNKLPSMAPKMacrophageNF-κBNONitric oxideNongenomic pathwayactivator protein 1bone marrow-derived macrophagesc-Jun NH(2)-terminal kinaseextracellular-regulated protein kinase 1/2iERinhibitory kappa Bintracellular estrogen receptorslipopolysaccharidemERmembrane estrogen receptorsmitogen-activated protein kinasenitric oxidenuclear factor-kappa B
医学主题词
动物(Animals);骨髓细胞(Bone Marrow Cells);细胞, 培养的(Cells, Cultured);雌二醇(Estradiol);雌激素受体调节剂(Estrogen Receptor Modulators);基因表达(Gene Expression);咪唑类(Imidazoles);JNK丝裂原活化蛋白激酶类(JNK Mitogen-Activated Protein Kinases);脂多糖类(Lipopolysaccharides);巨噬细胞(Macrophages);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);丝裂原活化蛋白激酶1(Mitogen-Activated Protein Kinase 1);丝裂原活化蛋白激酶3(Mitogen-Activated Protein Kinase 3);NF-κB(NF-kappa B);一氧化氮(Nitric Oxide);蛋白激酶抑制剂(Protein Kinase Inhibitors);吡啶类(Pyridines);血清白蛋白, 牛(Serum Albumin, Bovine);转录因子AP-1(Transcription Factor AP-1);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)
DOI
10.1016/j.cellimm.2013.11.004
PMID
24321566
发布时间
2022-03-17
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Cellular immunology
53-8页
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