Coenzyme Q10 prevents accelerated cardiac aging in a rat model of poor maternal nutrition and accelerated postnatal growth.
第一作者:
Jane L,Tarry-Adkins
第一单位:
University of Cambridge, Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome Trust - MRC Institute of Metabolic Science, Level 4, Box 289, Addenbrooke's Treatment Centre, Addenbrooke's Hospital, Cambridge CB2 OQQ, UK.
作者:
关键词
3-NT, 3-nitrotyrosine4-HNE, 4-hydroxynonenalBER, base excision repairBax, Bcl2-associated proteinCAST, computer assisted stereology toolbox.CVD, cardiovascular diseaseCellular senescenceCoQ, coenzyme QCuZnSOD, copper-zinc superoxide dismutaseDIG, dioxygeninDNA damageDevelopmental programmingETC, electron transport chainGPx, glutathione peroxidaseGR, glutathione reductaseMnSOD, manganese superoxide dismutaseNEIL1, nei endonuclease VIII-like 1NOX, nicotinamide adenine dinucleotide diphosphate oxidaseNTHL1, Nthl endonuclease III like-1O2, superoxide anionOGG-1, 8 oxoguanine DNA glycosylase 1OH-, hydroxy radicalsOxidative-stressPGFE, pulsed field gel electrophoresisPRDX, peroxidiredoxinRIS, reactive inflammatory speciesRNS, reactive nitrogen speciesROS, reactive oxidative speciesTelomere lengthUbiquinoneXO, xanthine oxidaseacta1, sarco endoplasmic reticulum Ca(2+) ATPaseactin, alpha-1nppa, natriuretic peptide Anppb, natriuretic peptide Bserca2, single strand breaks, SSBs
DOI
10.1016/j.molmet.2013.09.004
PMID
24327963
发布时间
2025-05-29
- 浏览89
Molecular metabolism
2013年2卷4期
480-90页
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