Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control.-论文-万方医学网

第一作者： Kathrina L,Marcelo

第一单位： Interdepartmental Program in Developmental Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Center for Cell and Gene Therapy, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Children's Nutrition Research Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

作者： Kathrina L,Marcelo ^[1] ; Tiffany M,Sills ^[2] ; Suleyman,Coskun ^[3] ; Hema,Vasavada ^[3] ; Supriya,Sanglikar ^[3] ; Lauren C,Goldie ^[1] ; Karen K,Hirschi ^[4]

作者单位： Interdepartmental Program in Developmental Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Center for Cell and Gene Therapy, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Children's Nutrition Research Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. ^[1] Interdisciplinary Program in Cell and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Center for Cell and Gene Therapy, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Children's Nutrition Research Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. ^[2] Yale Cardiovascular Research Center and Yale Stem Cell Center, Yale University School of Medicine, 300 George Street, New Haven, CT 06511, USA. ^[3] Interdepartmental Program in Developmental Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Interdisciplinary Program in Cell and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Center for Cell and Gene Therapy, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Children's Nutrition Research Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Yale Cardiovascular Research Center and Yale Stem Cell Center, Yale University School of Medicine, 300 George Street, New Haven, CT 06511, USA. Electronic address: karen.hirschi@yale.edu. ^[4]

主题词醛氧化还原酶类(Aldehyde Oxidoreductases);动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞分化(Cell Differentiation);核心结合因子α2亚基(Core Binding Factor Alpha 2 Subunit);周期素依赖激酶抑制剂p27(Cyclin-Dependent Kinase Inhibitor p27);胚胎培养技术(Embryo Culture Techniques);内皮细胞(Endothelial Cells);女(雌)性(Female);造血干细胞(Hematopoietic Stem Cells);乳糖操纵子(Lac Operon);慢病毒属(Lentivirus);男(雄)性(Male);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);妊娠(Pregnancy);原癌基因蛋白质类c-kit(Proto-Oncogene Proteins c-kit);原癌基因蛋白质c-myb(Proto-Oncogene Proteins c-myb);受体, Notch1(Receptor, Notch1);信号传导(Signal Transduction);维甲酸(Tretinoin)

DOI 10.1016/j.devcel.2013.11.004

PMID 24331925

发布时间 2021-10-21

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Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control.

Developmental cell

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Developmental cell

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Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control.

Developmental cell

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Developmental cell

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