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换一批
作者：
Frédéric,Ariey [1]
;
Benoit,Witkowski [2]
;
Chanaki,Amaratunga [3]
;
Johann,Beghain [1]
;
Anne-Claire,Langlois [4]
;
Nimol,Khim [2]
;
Saorin,Kim [2]
;
Valentine,Duru [2]
;
Christiane,Bouchier [5]
;
Laurence,Ma [5]
;
Pharath,Lim [6]
;
Rithea,Leang [7]
;
Socheat,Duong [7]
;
Sokunthea,Sreng [7]
;
Seila,Suon [7]
;
Char Meng,Chuor [7]
;
Denis Mey,Bout [8]
;
Sandie,Ménard [9]
;
William O,Rogers [10]
;
Blaise,Genton [11]
;
Thierry,Fandeur [12]
;
Olivo,Miotto [13]
;
Pascal,Ringwald [14]
;
Jacques,Le Bras [15]
;
Antoine,Berry [9]
;
Jean-Christophe,Barale [1]
;
Rick M,Fairhurst [16]
;
Françoise,Benoit-Vical [17]
;
Odile,Mercereau-Puijalon [18]
;
Didier,Ménard [19]
作者单位：
1] Institut Pasteur, Parasite Molecular Immunology Unit, 75724 Paris Cedex 15, France [2] Centre National de la Recherche Scientifique, Unité de Recherche Associée 2581, 75724 Paris Cedex 15, France [3] Institut Pasteur, Genetics and Genomics of Insect Vectors Unit, 75724 Paris Cedex 15, France (F.A.); Institut Pasteur, Functional Genetics of Infectious Diseases Unit, 75724 Paris Cedex 15, France (J.B.); Centre de Physiopathologie de Toulouse-Purpan, Institut National de la Santé et de la Recherche Médicale UMR1043, Centre National de la Recherche Scientifique UMR5282, Université Toulouse III, 31024 Toulouse Cedex 3, France Institut Pasteur, Unité de Biologie et Génétique du Paludisme, Team Malaria Targets and Drug Development, 75724 Paris Cedex 15, France (J.-C.B.).
[1]
Institut Pasteur du Cambodge, Malaria Molecular Epidemiology Unit, Phnom Penh, Cambodia.
[2]
Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
[3]
1] Institut Pasteur, Parasite Molecular Immunology Unit, 75724 Paris Cedex 15, France [2] Centre National de la Recherche Scientifique, Unité de Recherche Associée 2581, 75724 Paris Cedex 15, France.
[4]
Institut Pasteur, Plate-forme Génomique, Département Génomes et Génétique, 75724 Paris Cedex 15, France.
[5]
1] Institut Pasteur du Cambodge, Malaria Molecular Epidemiology Unit, Phnom Penh, Cambodia [2] Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA [3] National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.
[6]
National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.
[7]
SSA WHO, Drug Monitoring in Cambodia, National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.
[8]
1] Service de Parasitologie et Mycologie, Centre Hospitalier Universitaire de Toulouse, 31059 Toulouse Cedex 9, France [2] Institut Pasteur, Genetics and Genomics of Insect Vectors Unit, 75724 Paris Cedex 15, France (F.A.); Institut Pasteur, Functional Genetics of Infectious Diseases Unit, 75724 Paris Cedex 15, France (J.B.); Centre de Physiopathologie de Toulouse-Purpan, Institut National de la Santé et de la Recherche Médicale UMR1043, Centre National de la Recherche Scientifique UMR5282, Université Toulouse III, 31024 Toulouse Cedex 3, France Institut Pasteur, Unité de Biologie et Génétique du Paludisme, Team Malaria Targets and Drug Development, 75724 Paris Cedex 15, France (J.-C.B.).
[9]
Naval Medical Research Unit #2 Detachment, Phnom Penh, Cambodia.
[10]
Swiss Tropical and Public Health Institute, 4051 Basel, Switzerland.
[11]
1] Institut Pasteur, Parasite Molecular Immunology Unit, 75724 Paris Cedex 15, France [2] Institut Pasteur du Cambodge, Malaria Molecular Epidemiology Unit, Phnom Penh, Cambodia.
[12]
1] MRC Centre for Genomics and Global Health, University of Oxford, Oxford OX3 7BN, UK [2] Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok 10400, Thailand [3] Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
[13]
Global Malaria Program, World Health Organization, 1211 Geneva, Switzerland.
[14]
Centre National de Référence du Paludisme, CHU Bichat-Claude Bernard, APHP, PRES Sorbonne Paris Cité, 75018 Paris, France.
[15]
1] Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA [2].
[16]
1] Centre National de la Recherche Scientifique, Laboratoire de Chimie de Coordination UPR8241, 31077 Toulouse Cedex 4, France [2] Université de Toulouse, UPS, Institut National Polytechnique de Toulouse, 31077 Toulouse Cedex 4, France [3].
[17]
1] Institut Pasteur, Parasite Molecular Immunology Unit, 75724 Paris Cedex 15, France [2] Centre National de la Recherche Scientifique, Unité de Recherche Associée 2581, 75724 Paris Cedex 15, France [3].
[18]
1] Institut Pasteur du Cambodge, Malaria Molecular Epidemiology Unit, Phnom Penh, Cambodia [2].
[19]
主题词
等位基因(Alleles);动物(Animals);抗疟药(Antimalarials);青蒿素类(Artemisinins);血细胞(Blood Cells);柬埔寨(Cambodia);抗药性(Drug Resistance);遗传标记(Genetic Markers);半衰期(Half-Life);人类(Humans);疟疾, 恶性(Malaria, Falciparum);突变(Mutation);寄生虫敏感性试验(Parasitic Sensitivity Tests);恶性疟原虫(Plasmodium falciparum);多态性, 单核苷酸(Polymorphism, Single Nucleotide);蛋白质结构, 三级(Protein Structure, Tertiary);原虫蛋白质类(Protozoan Proteins);时间因素(Time Factors)
DOI
10.1038/nature12876
PMID
24352242
发布时间
2024-06-10
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Nature
Nature
50-5页
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