4-Hydroxy hexenal derived from dietary n-3 polyunsaturated fatty acids induces anti-oxidative enzyme heme oxygenase-1 in multiple organs.

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第一作者： Fumiyuki,Nakagawa

第一单位： Department of Medicine, Shiga University of Medical Science, Seta Tsukinowa-Cho, Otsu, Shiga 520-2192, Japan; Osaka Laboratory, JCL Bioassay Corporation, 5-16-26, Minamisuita, Suita-shi, Osaka 564-0043, Japan.

作者： Fumiyuki,Nakagawa ^[1] ; Katsutaro,Morino ^[2] ; Satoshi,Ugi ^[3] ; Atsushi,Ishikado ^[3] ; Keiko,Kondo ^[3] ; Daisuke,Sato ^[3] ; Shiho,Konno ^[4] ; Ken-ichi,Nemoto ^[3] ; Chisato,Kusunoki ^[3] ; Osamu,Sekine ^[3] ; Akihiro,Sunagawa ^[4] ; Masanori,Kawamura ^[4] ; Noriko,Inoue ^[4] ; Yoshihiko,Nishio ^[5] ; Hiroshi,Maegawa ^[3]

作者单位： Department of Medicine, Shiga University of Medical Science, Seta Tsukinowa-Cho, Otsu, Shiga 520-2192, Japan; Osaka Laboratory, JCL Bioassay Corporation, 5-16-26, Minamisuita, Suita-shi, Osaka 564-0043, Japan. ^[1] Department of Medicine, Shiga University of Medical Science, Seta Tsukinowa-Cho, Otsu, Shiga 520-2192, Japan. Electronic address: morino@belle.shiga-med.ac.jp. ^[2] Department of Medicine, Shiga University of Medical Science, Seta Tsukinowa-Cho, Otsu, Shiga 520-2192, Japan. ^[3] Osaka Laboratory, JCL Bioassay Corporation, 5-16-26, Minamisuita, Suita-shi, Osaka 564-0043, Japan. ^[4] Department of Diabetes and Endocrine Medicine, Division of Human and Environmental Sciences, Kagoshima University, Graduate School of Medical and Dental Sciences, Kagoshima, Japan. ^[5]

关键词 4-Hydroxy hexenal Docosahexaenoic acid (DHA)Heme oxygenase-1 Nuclear factor erythroid 2-related factor 2 (Nrf2)n-3 Polyunsaturated fatty acids (PUFAs)