T-type Ca2+ channel inhibition induces p53-dependent cell growth arrest and apoptosis through activation of p38-MAPK in colon cancer cells.
作者:
主题词
细胞凋亡(Apoptosis);Caco-2细胞(Caco-2 Cells);钙通道, T型(Calcium Channels, T-Type);细胞周期(Cell Cycle);细胞生长过程(Cell Growth Processes);细胞, 培养的(Cells, Cultured);结肠肿瘤(Colonic Neoplasms);基因敲低技术(Gene Knockdown Techniques);HCT116细胞(HCT116 Cells);人类(Humans);MAP激酶信号系统(MAP Kinase Signaling System);分子靶向治疗(Molecular Targeted Therapy);RNA, 小分子干扰(RNA, Small Interfering);转染(Transfection);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)
DOI
10.1158/1541-7786.MCR-13-0485
PMID
24362252
发布时间
2022-04-09
- 浏览18

Molecular cancer research
348-58页
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