Over-expressed copper/zinc superoxide dismutase localizes to mitochondria in neurons inhibiting the angiotensin II-mediated increase in mitochondrial superoxide.

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第一作者： Shumin,Li

第一单位： Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, USA.

作者： Shumin,Li ^[1] ; Adam J,Case ^[1] ; Rui-Fang,Yang ^[1] ; Harold D,Schultz ^[2] ; Matthew C,Zimmerman ^[2]

作者单位： Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, USA. ^[1] Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, USA ; Redox Biology Center, University of Nebraska - Lincoln, Lincoln, NE, USA. ^[2]

关键词 AT1R, angiotensin type 1 receptor AngII, angiotensin II Angiotensin II CuZnSOD CuZnSOD, copper/zinc superoxide dismutase Ikv, neuronal potassium current MIMS, mitochondrial inter-membrane space Mitochondria MnSOD, manganese superoxide dismutase NOX, NADPH oxidase Neurons Potassium current RAS, renin–angiotensin system ROS, reactive oxygen species Superoxide

主题词腺病毒科(Adenoviridae);血管紧张素Ⅱ(Angiotensin II);动物(Animals);细胞系(Cell Line);遗传载体(Genetic Vectors);小鼠(Mice);线粒体(Mitochondria);神经元(Neurons);膜片钳术(Patch-Clamp Techniques);信号传导(Signal Transduction);超氧化物歧化酶(Superoxide Dismutase);超氧化物类(Superoxides)

DOI 10.1016/j.redox.2013.11.002

PMID 24363997

发布时间 2021-10-21

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Redox biology

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Over-expressed copper/zinc superoxide dismutase localizes to mitochondria in neurons inhibiting the angiotensin II-mediated increase in mitochondrial superoxide.

Redox biology

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Redox biology

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Over-expressed copper/zinc superoxide dismutase localizes to mitochondria in neurons inhibiting the angiotensin II-mediated increase in mitochondrial superoxide.

Redox biology

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Redox biology

相关期刊

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