换一批
换一批A phase 1 study of prasugrel in patients with sickle cell disease: effects on biomarkers of platelet activation and coagulation.
第一作者：
Joseph A,Jakubowski
第一单位：
Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN USA. Electronic address: joseph@lilly.com.
作者：
关键词
ADPBiomarkersCD40 ligandCD40LEDTAGPIIbIIIaP2Y(12) receptor antagonistPDPKPlateletsPrasugrelRBCsSCDSDSickle cell diseaseTFTXB(2)VOCadenosine diphosphateethylenediaminetetraacetic acidglycoprotein IIb-IIIapharmacodynamicspharmacokineticsred blood cellssickle cell diseasestandard deviationthromboxane B(2)tissue factorvaso-occlusive crisis
主题词
腺苷二磷酸(Adenosine Diphosphate);成年人(Adult);贫血, 镰状细胞性(Anemia, Sickle Cell);血液凝固(Blood Coagulation);血小板(Blood Platelets);女(雌)性(Female);人类(Humans);男(雄)性(Male);中年人(Middle Aged);哌嗪类(Piperazines);血小板活化(Platelet Activation);嘌呤能P2Y受体拮抗剂(Purinergic P2Y Receptor Antagonists);噻吩类(Thiophenes);青年人(Young Adult)
DOI
10.1016/j.thromres.2013.12.008
PMID
24368019
发布时间
2022-01-29
- 浏览17
Thrombosis research
190-5页
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