SMILE inhibits BMP-2-induced expression of osteocalcin by suppressing the activity of the RUNX2 transcription factor in MC3T3E1 cells.
第一作者:
Hoon,Jang
第一单位:
Research Center of Integrative Cellulomics, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea; Functional Genomics, School of Engineering, University of Science and Technology (UST), Daejeon 305-806, Republic of Korea.
作者:
医学主题词
动物(Animals);碱性亮氨酸拉链转录因子类(Basic-Leucine Zipper Transcription Factors);印迹法, 蛋白质(Blotting, Western);骨形态发生蛋白质2(Bone Morphogenetic Protein 2);细胞分化(Cell Differentiation);染色质免疫沉淀法(Chromatin Immunoprecipitation);核心结合因子α1亚基(Core Binding Factor Alpha 1 Subunit);基因表达调控(Gene Expression Regulation);人类(Humans);小鼠(Mice);成骨细胞(Osteoblasts);骨钙素(Osteocalcin);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction)
DOI
10.1016/j.bone.2013.12.028
PMID
24389415
发布时间
2014-03-03
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