Multiplexing high-content flow (HCF) and quantitative high-throughput screening (qHTS) to identify compounds capable of decreasing cell viability, activating caspase 3/7, expressing annexin V, and changing mitochondrial membrane integrity.
第一作者:
Lesley A,Mathews
第一单位:
Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland.
作者:
医学主题词
膜联蛋白A5(Annexin A5);细胞凋亡(Apoptosis);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);半胱氨酸天冬氨酸蛋白酶7(Caspase 7);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);剂量效应关系, 药物(Dose-Response Relationship, Drug);酶激活(Enzyme Activation);流式细胞术(Flow Cytometry);高通量筛选分析(High-Throughput Screening Assays);人类(Humans);线粒体膜(Mitochondrial Membranes)
DOI
10.1002/9780470559277.ch130060
PMID
24391083
发布时间
2014-01-06
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