Syndecan-1 (CD138) modulates triple-negative breast cancer stem cell properties via regulation of LRP-6 and IL-6-mediated STAT3 signaling.
第一作者:
Sherif A,Ibrahim
第一单位:
Department of Gynecology and Obstetrics, University Hospital Münster, Münster, Germany ; Department of Zoology, Faculty of Science, Cairo University, Giza, Egypt.
作者:
医学主题词
细胞分化(Cell Differentiation);减量调节(Down-Regulation);基因敲低技术(Gene Knockdown Techniques);基因沉默(Gene Silencing);人类(Humans);白细胞介素6(Interleukin-6);同工酶类(Isoenzymes);NF-κB(NF-kappa B);肿瘤干细胞(Neoplastic Stem Cells);RNA, 小分子干扰(RNA, Small Interfering);视黄醛脱氢酶(Retinal Dehydrogenase);STAT3转录因子(STAT3 Transcription Factor);信号传导(Signal Transduction);球形体, 细胞(Spheroids, Cellular);多配体蛋白聚糖1(Syndecan-1);Wnt蛋白质类(Wnt Proteins)
DOI
10.1371/journal.pone.0085737
PMID
24392029
发布时间
2021-10-21
- 浏览39
PloS one
e85737页
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