GPCR-like signaling mediated by smoothened contributes to acquired chemoresistance through activating Gli.
第一作者:
Xia,Zhan
第一单位:
Department of Pharmacology, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, P,R, China. wftan@fudan.edu.cn.
作者:
医学主题词
抗肿瘤药(Antineoplastic Agents);印迹法, 蛋白质(Blotting, Western);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);抗药性, 肿瘤(Drug Resistance, Neoplasm);人类(Humans);肿瘤(Neoplasms);受体, G-蛋白偶联(Receptors, G-Protein-Coupled);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);信号传导(Signal Transduction);转录因子(Transcription Factors)
DOI
10.1186/1476-4598-13-4
PMID
24393163
发布时间
2021-10-21
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