A Multiplexed Fluorescent Calcium and NFAT Reporter Gene Assay to Identify GPCR Agonists.

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作者： Heeral,Sheth ^[1] ; Colleen,Gorey ^[2] ; Nicole,Roush ^[3] ; Shelly,Smallman ^[3] ; Elizabeth,Collantes ^[3] ; Maxine,Santoro ^[3] ; Barbara,Olson ^[3] ; Laura,Fitzgerald ^[3] ; Paul H,Lee ^[4] ; Xiqiang John,Shen ^[3]

作者单位： Lawrence Livermore National Laboratory, Livermore, CA 94550, USA. ^[1] Department of Chemical and Environmental Engineering, University of Toledo, Toledo OH 43606, USA. ^[2] Pfizer Global Research and Development, Groton Laboratories, Groton, CT 06340, USA. ^[3] Amgen, Inc., Lead Discovery, Thousand Oaks, CA 91320, USA. ^[4]

关键词 FLIPR assay GPCR beta-lactamase reporter gene assay fluorescent calcium assay high throughput screening multiplex assay.

DOI 10.2174/2213988501307010001

PMID 24396729

发布时间 2021-10-21

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Current chemical genomics and translational medicine

2013年7卷

1-8页

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A Multiplexed Fluorescent Calcium and NFAT Reporter Gene Assay to Identify GPCR Agonists.

Current chemical genomics and translational medicine

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A Multiplexed Fluorescent Calcium and NFAT Reporter Gene Assay to Identify GPCR Agonists.

Current chemical genomics and translational medicine

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Current chemical genomics and translational medicine

相关期刊

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