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首页> Cellular signalling> Activated PLC-γ1 is catalytically induced at LAT but activated PLC-γ1 is localized at both LAT- and TCR-containing complexes.

Activated PLC-γ1 is catalytically induced at LAT but activated PLC-γ1 is localized at both LAT- and TCR-containing complexes.

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作者： Noemi,Cruz-Orcutt ^[1] ; Aldo,Vacaflores ^[2] ; Sean F,Connolly ^[2] ; Stephen C,Bunnell ^[3] ; Jon C D,Houtman ^[4]

作者单位： Department of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, United States. ^[1] Interdisciplinary Graduate Program in Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, United States. ^[2] Program in Immunology, Sackler School of Graduate Biomedical Sciences, Boston, MA 02111, United States; Department of Pathology, Tufts University School of Medicine, Boston, MA 02111, United States. ^[3] Department of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, United States; Interdisciplinary Graduate Program in Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, United States. Electronic address: jon-houtman@uiowa.edu. ^[4]

关键词 Grb2 LAT PLC-γ1 Phosphorylation kinetics TCR

主题词衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);GRB2衔接蛋白质(GRB2 Adaptor Protein);人类(Humans);Jurkat细胞(Jurkat Cells);动力学(Kinetics);膜蛋白质类(Membrane Proteins);磷脂酶Cγ(Phospholipase C gamma);磷酰化(Phosphorylation);蛋白质结合(Protein Binding);受体, 抗原, T细胞(Receptors, Antigen, T-Cell);信号传导(Signal Transduction);T淋巴细胞(T-Lymphocytes)

DOI 10.1016/j.cellsig.2013.12.022

PMID 24412752

发布时间 2021-10-21

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Cellular signalling

Cellular signalling

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