Ecology- and bioassay-guided drug discovery for treatments of tropical parasitic disease: 5alpha,8alpha-epidioxycholest-6-en-3beta-ol isolated from the mollusk Dolabrifera dolabrifera shows significant activity against Leishmania donovani.
第一作者:
Kathryn E,Clark
第一单位:
Smithsonian Tropical Research Institute, Apartado 2072, Balboa Ancón, Republic of Panama.
作者:
医学主题词
动物(Animals);抗原虫药(Antiprotozoal Agents);生物学鉴定法(Biological Assay);药物发现(Drug Discovery);麦角固醇(Ergosterol);杜氏利什曼原虫(Leishmania donovani);软体动物门(Mollusca)
PMID
24427935
发布时间
2014-01-16
- 浏览14
Natural product communications
1537-40页
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