换一批Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors.
第一作者：
Jack F,Shern
第一单位：
1Pediatric Oncology Branch, Oncogenomics Section, Center for Cancer Research, NIH; 2Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland; 3Broad Institute of MIT and Harvard, Cambridge; 4Medical Oncology and Center for Cancer Genome Discovery, Dana-Farber Cancer Institute; 5Department of Pathology, Harvard Medical School, Boston, Massachusetts; 6University of Nebraska Medical Center, Omaha, Nebraska; 7Department of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas; and 8Department of Pediatrics, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington; 9The Tumour Bank, The Children's Cancer Research Unit, The Children's Hospital at Westmead, Westmead, New South Wales, Australia; 10Department of Oncology, Hospital Sant Joan de Deu de Barcelona, Barcelona, Spain.
作者：
医学主题词
动物(Animals);细胞周期蛋白质类(Cell Cycle Proteins);染色体畸变(Chromosome Aberrations);I类磷脂酰肌醇3-激酶类(Class I Phosphatidylinositol 3-Kinases);聚类分析(Cluster Analysis);DNA拷贝数变异(DNA Copy Number Variations);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因重排(Gene Rearrangement);基因调控网络(Gene Regulatory Networks);全基因组关联研究(Genome-Wide Association Study);基因组学(Genomics);基因型(Genotype);人类(Humans);小鼠(Mice);突变(Mutation);癌基因蛋白质类, 融合(Oncogene Proteins, Fusion);成对盒转录因子类(Paired Box Transcription Factors);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));受体, 成纤维细胞生长因子(Receptors, Fibroblast Growth Factor);横纹肌肉瘤(Rhabdomyosarcoma);信号传导(Signal Transduction)
DOI
10.1158/2159-8290.CD-13-0639
PMID
24436047
发布时间
2025-05-29
- 浏览122
Cancer discovery
216-31页
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