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Missense variant in TREML2 protects against Alzheimer's disease.

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作者单位: Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. [1] Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA. [2] Diagnostic Discovery Department, Genentech Inc, South San Francisco, CA, USA. [3] Human Genetics, School of Molecular Medical Sciences, University of Nottingham, Nottingham, UK. [4] Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK. [5] Inserm, Lille, France; Universite Lille 2, Lille, France; Institut Pasteur de Lille, Lille, France. [6] Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK. [7] Institute of Psychiatry, King's College London, London, UK. [8] Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, CA, USA. [9] Human Genetics Department, Genentech Inc, South San Francisco, CA, USA. [10] Department of Neurology, Taub Institute on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA. [11] The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA; Dr John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, FL, USA. [12] Department of Medicine, Boston University Schools of Medicine and Public Health, Boston, MA, USA; Department of Biomedical Genetics, Boston University Schools of Medicine and Public Health, Boston, MA, USA; Department of Neurology, Boston University Schools of Medicine and Public Health, Boston, MA, USA; Department of Ophthalmology, Boston University Schools of Medicine and Public Health, Boston, MA, USA; Department of Epidemiology, Boston University Schools of Medicine and Public Health, Boston, MA, USA; Department of Biostatistics, Boston University Schools of Medicine and Public Health, Boston, MA, USA. [13] Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. [14] Department of Molecular Physiology and Biophysics, Vanderbilt Center for Human Genetics Research, Vanderbilt University, Nashville, TN, USA. [15] Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. [16] Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. [17] Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. [18] Department of Biology, Brigham Young University, Provo, UT, USA. [19] Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: goatea@psychiatry.wustl.edu. [20] Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA; Universite Lille 2, Lille, France. Electronic address: cruchagac@psychiatry.wustl.edu. [21]
DOI 10.1016/j.neurobiolaging.2013.12.010
PMID 24439484
发布时间 2023-02-28
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