换一批Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma.
第一作者：
Fengting,Yan
第一单位：
Authors' Affiliations: Division of Hematology, Department of Internal Medicine; Division of Infectious Diseases, Department of Internal Medicine; Departments of Neurosurgery; Molecular and Cellular Biochemistry; Chemical Engineering; Statistics; Pathology; Radiation Oncology; and College of Pharmacy, The Ohio State University (OSU), Columbus; Case Comprehensive Cancer Center; and Department of Epidemiology and Biostatistics, CWRU School of Medicine, Cleveland, Ohio.
作者：
医学主题词
动物(Animals);细胞凋亡(Apoptosis);脑肿瘤(Brain Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);基因表达(Gene Expression);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因敲低技术(Gene Knockdown Techniques);胶质母细胞瘤(Glioblastoma);人类(Humans);Kaplan-Meiers评估(Kaplan-Meier Estimate);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);小鼠, 裸(Mice, Nude);分子靶向治疗(Molecular Targeted Therapy);肿瘤移植(Neoplasm Transplantation);蛋白质精氨酸N-甲基转移酶(Protein-Arginine N-Methyltransferases);RNA, 小分子干扰(RNA, Small Interfering);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)
DOI
10.1158/0008-5472.CAN-13-0884
PMID
24453002
发布时间
2026-03-06
- 浏览75
Cancer research
1752-65页
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