Design, synthesis, and biological evaluation of deuterated C-aryl glycoside as a potent and long-acting renal sodium-dependent glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes.
第一作者:
Ge,Xu
第一单位:
School of Pharmacy, Fudan University , 826 Zhangheng Road, Pudong New Area, Shanghai 201203, P. R. China.
作者:
医学主题词
动物(Animals);糖尿病, 2型(Diabetes Mellitus, Type 2);糖苷类(Glycosides);磁共振波谱学(Magnetic Resonance Spectroscopy);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);钠-葡萄糖转运体2(Sodium-Glucose Transporter 2);光谱法, 质量, 电喷雾电离(Spectrometry, Mass, Electrospray Ionization)
DOI
10.1021/jm401780b
PMID
24456245
发布时间
2019-12-10
- 浏览250
Journal of medicinal chemistry
1236-51页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文


换一批



