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Polymorphisms in BACE2 may affect the age of onset Alzheimer's dementia in Down syndrome.

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第一作者： Kin Y,Mok

第一单位： Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK; Reta Lila Weston Institute, UCL Institute of Neurology, London, UK. Electronic address: k.mok@ucl.ac.uk.

作者： Kin Y,Mok ^[1] ; Emma L,Jones ^[2] ; Marisa,Hanney ^[3] ; Denise,Harold ^[4] ; Rebecca,Sims ^[4] ; Julie,Williams ^[4] ; Clive,Ballard ^[2] ; John,Hardy ^[5]

作者单位： Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK; Reta Lila Weston Institute, UCL Institute of Neurology, London, UK. Electronic address: k.mok@ucl.ac.uk. ^[1] Wolfson Centre for Age-Related Diseases, King's College London, London, UK. ^[2] Northgate Hospital, Morpeth, Northumberland, UK. ^[3] MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Henry Wellcome Building for Biomedical Research, Heath Park, Cardiff, UK. ^[4] Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK; Reta Lila Weston Institute, UCL Institute of Neurology, London, UK; The London Down Syndrome (LonDownS) Consortium, UK. ^[5]

关键词 Alzheimer's disease BACE2 Down syndrome rs2252576