A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes.-论文-万方医学网

第一作者： Johan,Larsbrink

第一单位： 1] Division of Glycoscience, School of Biotechnology, Royal Institute of Technology (KTH), AlbaNova University Centre, 106 91 Stockholm, Sweden [2].

作者： Johan,Larsbrink ^[1] ; Theresa E,Rogers ^[2] ; Glyn R,Hemsworth ^[3] ; Lauren S,McKee ^[4] ; Alexandra S,Tauzin ^[5] ; Oliver,Spadiut ^[4] ; Stefan,Klinter ^[6] ; Nicholas A,Pudlo ^[7] ; Karthik,Urs ^[7] ; Nicole M,Koropatkin ^[7] ; A Louise,Creagh ^[8] ; Charles A,Haynes ^[8] ; Amelia G,Kelly ^[7] ; Stefan Nilsson,Cederholm ^[6] ; Gideon J,Davies ^[9] ; Eric C,Martens ^[7] ; Harry,Brumer ^[10]

作者单位： 1] Division of Glycoscience, School of Biotechnology, Royal Institute of Technology (KTH), AlbaNova University Centre, 106 91 Stockholm, Sweden [2]. ^[1] 1] Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA [2]. ^[2] 1] Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, UK [2]. ^[3] 1] Division of Glycoscience, School of Biotechnology, Royal Institute of Technology (KTH), AlbaNova University Centre, 106 91 Stockholm, Sweden [2] Wallenberg Wood Science Center, Royal Institute of Technology (KTH), Teknikringen 56-58, 100 44 Stockholm, Sweden. ^[4] Michael Smith Laboratories and Department of Chemistry, University of British Columbia, 2185 East Mall, Vancouver, British Columbia V6T 1Z4, Canada. ^[5] Division of Glycoscience, School of Biotechnology, Royal Institute of Technology (KTH), AlbaNova University Centre, 106 91 Stockholm, Sweden. ^[6] Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA. ^[7] Michael Smith Laboratories and Department of Chemical and Biological Engineering, University of British Columbia, 2185 East Mall, Vancouver, British Columbia V6T 1Z4, Canada. ^[8] Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, UK. ^[9] 1] Division of Glycoscience, School of Biotechnology, Royal Institute of Technology (KTH), AlbaNova University Centre, 106 91 Stockholm, Sweden [2] Michael Smith Laboratories and Department of Chemistry, University of British Columbia, 2185 East Mall, Vancouver, British Columbia V6T 1Z4, Canada. ^[10]

主题词氨基酸序列(Amino Acid Sequence);拟杆菌属(Bacteroides);碳水化合物代谢(Carbohydrate Metabolism);碳水化合物序列(Carbohydrate Sequence);细胞壁(Cell Wall);结晶学, X线(Crystallography, X-Ray);膳食(Diet);膳食纤维(Dietary Fiber);进化, 分子(Evolution, Molecular);胃肠道(Gastrointestinal Tract);基因座(Genetic Loci);葡聚糖类(Glucans);糖苷水解酶类(Glycoside Hydrolases);人类(Humans);宏基因组(Metagenome);模型, 分子(Models, Molecular);分子序列数据(Molecular Sequence Data);种系发生(Phylogeny);蛋白质结构, 三级(Protein Structure, Tertiary);共生(Symbiosis);木聚糖类(Xylans)

DOI 10.1038/nature12907

PMID 24463512

发布时间 2024-05-22

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A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes.

Nature

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A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes.

Nature

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