换一批
换一批pTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: involvement of non-receptor type 1 protein tyrosine phosphatase (PTPN1).
第一单位：
Department of Pediatrics, Steele Children's Research Center, University of Arizona Health Sciences Center, Tucson, Arizona, United States of America.
作者：
主题词
腺癌(Adenocarcinoma);抗肿瘤药(Antineoplastic Agents);印迹法, 蛋白质(Blotting, Western);连环素类(Catenins);细胞系, 肿瘤(Cell Line, Tumor);细胞膜(Cell Membrane);细胞运动(Cell Movement);结直肠肿瘤(Colorectal Neoplasms);皮动蛋白(Cortactin);姜黄素(Curcumin);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);HCT116细胞(HCT116 Cells);HT29细胞(HT29 Cells);人类(Humans);免疫组织化学(Immunohistochemistry);显微镜检查, 共焦(Microscopy, Confocal);磷酰化(Phosphorylation);蛋白质结合(Protein Binding);蛋白质加工, 转译后(Protein Processing, Post-Translational);蛋白质酪氨酸磷酸酶, 非受体1型(Protein Tyrosine Phosphatase, Non-Receptor Type 1);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);酪氨酸(Tyrosine)
DOI
10.1371/journal.pone.0085796
PMID
24465712
发布时间
2022-12-07
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