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Tumor exosomes induce tunneling nanotubes in lipid raft-enriched regions of human mesothelioma cells.

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第一作者： Venugopal,Thayanithy

第一单位： Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN 55455, USA.

作者： Venugopal,Thayanithy ^[1] ; Victor,Babatunde ^[2] ; Elizabeth L,Dickson ^[3] ; Phillip,Wong ^[1] ; Sanghoon,Oh ^[4] ; Xu,Ke ^[4] ; Afsar,Barlas ^[4] ; Sho,Fujisawa ^[4] ; Yevgeniy,Romin ^[4] ; André L,Moreira ^[5] ; Robert J,Downey ^[6] ; Clifford J,Steer ^[7] ; Subbaya,Subramanian ^[8] ; Katia,Manova-Todorova ^[4] ; Malcolm A S,Moore ^[2] ; Emil,Lou ^[9]

作者单位： Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN 55455, USA. ^[1] Moore Laboratory, Department of Cell Biology, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. ^[2] Department of Obstetrics & Gynecology, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN 55455, USA. ^[3] Molecular Cytology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. ^[4] Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. ^[5] Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. ^[6] Departments of Medicine and Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA. ^[7] Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA. ^[8] Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: emil-lou@umn.edu. ^[9]

关键词 Exosomes Intercellular communication Intercellular transfer Lipid rafts Mesothelioma Tunneling nanotubes

医学主题词生物转运(Biological Transport);细胞间通讯(Cell Communication);细胞培养技术(Cell Culture Techniques);细胞系, 肿瘤(Cell Line, Tumor);外泌体(Exosomes);人类(Humans);膜微区(Membrane Microdomains);间皮瘤(Mesothelioma);纳米管(Nanotubes);信号传导(Signal Transduction);肿瘤微环境(Tumor Microenvironment)

DOI 10.1016/j.yexcr.2014.01.014

PMID 24468420

发布时间 2021-10-21

基金项目

5T32-CA132715/CA/NCI NIH HHS/United States P30 CA008748/CA/NCI NIH HHS/United States 8UL1TR000114/TR/NCATS NIH HHS/United States UL1 TR000114/TR/NCATS NIH HHS/United States KL2 TR000113/TR/NCATS NIH HHS/United States

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