Characterization of SM201, an anti-hFcγRIIB antibody not interfering with ligand binding that mediates immune complex dependent inhibition of B cells.
第一作者:
N,Rieth
第一单位:
SuppreMol GmbH, Martinsried, Germany.
作者:
医学主题词
动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);抗体亲和力(Antibody Affinity);抗体特异性(Antibody Specificity);抗原抗体复合物(Antigen-Antibody Complex);B-淋巴细胞(B-Lymphocytes);CHO细胞(CHO Cells);细胞系, 肿瘤(Cell Line, Tumor);仓鼠属(Cricetulus);基因表达调控(Gene Expression Regulation);人类(Humans);杂交瘤(Hybridomas);免疫球蛋白G(Immunoglobulin G);配体(Ligands);蛋白质结合(Protein Binding);大鼠(Rats);受体, 抗原, B细胞(Receptors, Antigen, B-Cell);受体, IgG(Receptors, IgG);重组融合蛋白质类(Recombinant Fusion Proteins);信号传导(Signal Transduction)
DOI
10.1016/j.imlet.2014.01.012
PMID
24472604
发布时间
2014-06-16
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Immunology letters
145-50页
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