Phosphorylation-regulated degradation of the tumor-suppressor form of PED by chaperone-mediated autophagy in lung cancer cells.
第一作者:
Cristina,Quintavalle
第一单位:
Department of Molecular Medicine and Medical Biotechnology, "Federico II" University of Naples, Naples, Italy; Institute of Endocrinology and Experimental Oncology "G. Salvatore" (IEOS), Consiglio Nazionale delle Ricerche (CNR), Naples, Italy.
作者:
医学主题词
氨基酸特征结构(Amino Acid Motifs);动物(Animals);凋亡调节蛋白质类(Apoptosis Regulatory Proteins);自噬(Autophagy);细胞系, 肿瘤(Cell Line, Tumor);HEK293细胞(HEK293 Cells);HSC70热休克蛋白质类(HSC70 Heat-Shock Proteins);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);肺肿瘤(Lung Neoplasms);溶酶体(Lysosomes);男(雄)性(Male);磷蛋白类(Phosphoproteins);磷酰化(Phosphorylation);蛋白质结合(Protein Binding);蛋白质转运(Protein Transport);RNA干扰(RNA Interference);大鼠(Rats);大鼠, Wistar(Rats, Wistar);重组蛋白质类(Recombinant Proteins);信号传导(Signal Transduction);时间因素(Time Factors);转染(Transfection);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)
DOI
10.1002/jcp.24569
PMID
24477641
发布时间
2022-01-12
基金项目
P01 AG031782/AG/NIA NIH HHS/United States
P30 AG038072/AG/NIA NIH HHS/United States
AG031782/AG/NIA NIH HHS/United States
AG03872/AG/NIA NIH HHS/United States
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